He tino ngawari te tātaritanga o te acromegaly (engari ka whakaarohia e koe), na te mea he whakamatautau toto hei whakatau i te taumata o te GH me te IGF-1. I roto i te acromegaly, he nui te taumata o te IGF-1 me te GH, me te mohio ko te hunanga o te GH he waahi noa, engari i roto i te acromegaly he tiketike tonu na te mea kua kore e whakahaerehia. Ko te taatutanga taiwhanga tuturu kei runga i te whakamatautau huka. I te mea ka whakaheke te hukahuka i te hunanga o te GH, ka taea e te whakahaere waha o te hukahuka te kite, ma nga whakamatautau toto e whai ake nei, i roto i te acromegaly, kei te kaha tonu te whakaputanga o te homoni tupu.

Ina whakapumautia te hypersecretion o te GH, katahi ka tika kia kitea tona takenga. I tenei ra, ko te paerewa koura he MRI o te roro ka whakaatu pea he puku pituitary gland. I roto i nga take tino onge, he puku kei etahi atu wahi (te nuinga o te wa kei roto i te roro, te huhu, te pancreas ranei) e huna ana i tetahi atu homoni e mahi ana ki te repe pituitary, GHRH, e whakaihiihi ana i te hanga o te GH. Ka mahia he aromatawai whanui ake kia kitea te takenga mai o tenei hunanga kino.